About the performance and use of 3-indolycarbinol

Indol 3 Carbinol of carbinol

Easy to decompose in light and air, not resistant to storage. It is safe for people and animals. Soluble in hot water, ethanol, acetone, ether and ethyl acetate, slightly soluble in water, benzene and chloroform; stable in alkaline solution, soluble in a small amount of 95% alcohol when using pure product crystallization preparation, and then dissolved in water to the appropriate amount.

Use of 3-Indolylcarbinol

Used as plant growth stimulant and analytical reagent. Indole-3-Methanol, 3-indoleacetaldehyde, 3,3'-Diindolylmethane, ascorbic acid and other auxin exist naturally in nature. Tryptophan is the precursor of 3-indoleacetic acid biosynthesis in plants. The basic function of auxin is to regulate plant growth. It can not only promote growth, but also inhibit growth and organ building. Auxin not only exists in free state in plant cells, but also exists in bound auxin which can be firmly combined with biopolymers and other special substances, such as indoleacetyl asparagine, pentose indoleacetate and indoleacetylglucose. This may be a storage way of auxin in cells, and it is also an detoxification way to eliminate the toxicity of excessive auxin.

Indole-3-methanol in vegetables may block the production of colon cancer(1)

In a new study, researchers from the Francis crick institute(Red Cabbage Powder) in the UK found that chemicals produced by vegetables such as kale, Red Cabbage Dye, cabbage and broccoli may help maintain a healthy gut and prevent colon cancer from developing. Related research results published on August 21, 2018, The Immunity of The journal, The paper entitled "The Environmental Sensor AHR Protects The from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity, 3-Indolylcarbinol".

The study confirmed that mice fed a diet rich in indole-3-carbinol (Indol 3 Carbinol) were protected from intestinal inflammation and colon cancer. I3C can also be produced when we ingested genus Brassica.

While the health benefits of vegetables are well established, many of the mechanisms behind them remain unknown. The study provides the first concrete evidence to prove how diet of I3C can by activating receptors called an aromatic (Indole-3-Methanol, AhR) protein to prevent inflammation and colon cancer.