2020年6月20日星期六

Background and overview of mango leaf extract(2)

Mangiferin can improve hyperinsulinemia of KK-Ay mice. Flax lignans Based on the above results, mangiferin may show antidiabetic activity through insulin sensitization.
In the prior art, the preparation method of Mango Leaf Extract adopts the method of concentration and drying after extraction. The content of mangiferin is low, which belongs to the crude method with low potency. The refining Mangiferin include the use of macroporous adsorption resin or silica gel chromatography. Silica gel chromatography is not suitable for large-scale production with a large number of organic solvents. In the past, the purification method of macroporous adsorption resin used high concentration ethanol for elution, but it is difficult to get Gardenia Yellow leaf extract with mangiferin content of more than 50%. More importantly, the eluted mango leaf extract can not be prevented The effect of diabetes and lipid-lowering.

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